Long-Term Impact of Military-Relevant Brain Injury Consortium Chronic Effects of Neurotrauma Consortium

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COVID-19 Update

The majority of the LIMBIC-CENC program remain fully operational since the initiation of COVID-19 pandemic and mitigation steps. For specific information on impact of COVID-19 on LIMBIC-CENC, please click on the relevant FAQ(s) below:

  • For individuals already enrolled in the CENC (now known as LIMBIC-CENC) Prospective Longitudinal Study (PLS)
   How does COVID-19 impact my study participation?

Until further notice, all LIMBIC-CENC PLS enrollment and testing sites have temporarily paused in-person, face-to-face data collection. If you are currently in your window for an In-Person Follow-Up, you will be contacted in order to conduct your visit over the telephone with some aspects by mail-back. This telephone visit will take the place of your regularly scheduled in-person visit. If this is a year in which you were scheduled for a Telephone Follow-Up, there are no changes; you will still receive the usual call from the LIMBIC-CENC call center. Once our enrollment and testing sites are cleared to restart face-to-face research again, we will resume the normal schedule for conducting In-Person Follow-Ups. This might include trying to schedule any portions of the in-person visit that were missed if you did the back-up phone and mail portions during the COVID-19 pandemic face-to-face research restriction.

  • For Service Members and Veterans interested in volunteering to join the LIMBIC-CENC Prospective Longitudinal Study (PLS)
   Does COVID-19 delay my participation?

Yes. In-person research has been paused at all LIMBIC-CENC enrollment and testing sites so we are not currently able to enroll new participants. However, as soon as the pause is lifted, we will restart enrolling and we will need new participants to join the study. While we are awaiting the “all clear” to initiate face-to-face testing, we encourage you to contact the site nearest you and give your contact information so that they can reach out to you once testing resumes. Click here to find the LIMBIC-CENC site nearest you.

  • For LIMBIC-CENC research team members and LIMBIC-CENC Government Steering Committee members needing more information on the multicenter PLS
   Login to internal site to view content

  • For LIMBIC-CENC Retrospective (Epidemiology) Study Operations
   Is there any impact?

The LIMBIC-CENC Epidemiology Project, consisting of three complementary research arms led by Drs. Yaffe, Pugh and Dismuke, has had no significant impact on its comprehensive analyses of stored mega-data from 7 federal (VA, DoD, CMS) datasets containing information from 2001-2019 on more than 2 million active duty and Veteran service members.

  • For Researchers wishing to collaborate with LIMBIC-CENC
   Click here for additional information:

  • Please contact the Coordinating Center ( or or directly to any of our leadership team if you have a collaboration interest.
  • Please note that LIMBIC-CENC PLS uploads all of its data into FITBIR (

The U.S. Army Medical Research Acquisition Activity, 839 Chandler Street, Fort Detrick MD 21702-5014 is the awarding and administering acquisition office. This work was supported by the Assistant Secretary of Defense for Health Affairs endorsed by the Department of Defense, through the Psychological Health/Traumatic Brain Injury Research Program Long-Term Impact of Military-Relevant Brain Injury Consortium (LIMBIC) Award/W81XWH-18-PH/TBIRP-LIMBIC under Awards No. W81XWH1920067 and W81XWH-13-2-0095, and by the U.S. Department of Veterans Affairs Awards No. I01 CX002097, I01 CX002096, I01 HX003155, I01 RX003444, I01 RX003443, I01 RX003442, I01 CX001135, I01 CX001246, I01 RX001774, I01 RX 001135, I01 RX 002076, I01 RX 001880, I01 RX 002172, I01 RX 002173, I01 RX 002171, I01 RX 002174, and I01 RX 002170. Opinions, interpretations, conclusions and recommendations are those of the author and are not necessarily endorsed by the Department of Defense. / Created by VCU University Relations

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